Asthma affects 8 percent of the U.S. population. Severe asthma—the symptoms of which are difficult to manage despite high doses of medicines, like corticosteroids—accounts for most healthcare costs due to its complexity to treat. New therapies are needed to eliminate symptoms of this life-threatening disease. Ben Gaston, the Billie Lou Wood Professor of Pediatrics at… Read more »
Tag: IU School of Medicine
Patents awarded to four IU innovations
Four Indiana University-led technologies and methods, spanning the fields of electrical engineering, medicine and music, recently received patents from the U.S. Patent and Trademark Office. Below is information about each patent. Patent issued to IU innovation method for treating clinical conditions through the use of hematopoietic stem cells: The U.S. Patent and Trademark Office has… Read more »
IU researcher develops treatments for neurotrophic keratopathy and device to test corneal sensation
IU School of Medicine professor’s discoveries could transform the treatment of a rare eye disorder that can lead to blindness. Affecting 1 in 2,000 people, neurotrophic keratopathy is a rare cause of blindness caused by a lack of nerve supply to the cornea. Patients with neurotrophic keratopathy experience a loss of sensation in the surface… Read more »
IU researcher developing new pediatric leukemia therapies
Pediatric leukemia affects approximately 4,000 children each year in the United States, and the incidence of the disease is steadily increasing year after year. Reuben Kapur, director of the Herman B Wells Center for Pediatric Research at the Indiana University School of Medicine, is working to discover new treatments that will improve patient care. He… Read more »
IU researcher develops innovation to combat increasing mosquito insecticide resistance, mosquito-borne diseases
Mosquito-borne infectious diseases like malaria, which claims half a million lives a year, have been on the rise over the past several years and pose a significant threat to global health. Even with the availability of many viable chemistries, there is a pressing need for new and innovative solutions to address insecticide resistance, mitigate environmental… Read more »
Patents awarded to six IU innovations
Six Indiana University-led technologies and methods have recently received patents from the U.S. Patent and Trademark Office. These innovations include an antiviral drug treatment for HPV, as well as methods for activating T cells in vitro, processing speech, enhancing the study of the gut microbial ecosystem, analyzing lipoproteins through the use of mass spectrometry and… Read more »
IU researcher pioneers new class of antibiotics to treat infectious diseases
An Indiana University researcher is pioneering an innovative approach to develop new antibiotics that could help address the growing problem of bacterial antimicrobial resistance, which is when bacteria and viruses no longer respond to antibiotic medicines. Recent estimates indicate that each year there are 5 million infections globally associated with bacterial antimicrobial resistance, with 1.3… Read more »
IU researcher uses revolutionary method to develop anticancer therapeutics
When developing anticancer therapeutics, most researchers aim to kill cancerous cells. However, Hiroki Yokota’s approach is to control their growth by knowing how to grow them. Yokota, a professor of biomedical engineering at the School of Engineering and Technology at IUPUI, an adjunct professor of anatomy, cell biology and physiology at the IU School of… Read more »
IU researcher’s drug to slow diabetic retinopathy successfully completes Phase 2 trial
Mark R. Kelley, the Betty and Earl Herr professor of pediatric oncology research at the Indiana University School of Medicine and associate director of basic science at the IU Melvin and Bren Simon Comprehensive Cancer Center, is celebrating the positive Phase 2 trial results of a first-of-its-kind drug he developed to slow the progression of… Read more »
IU researchers create gene therapeutic for the treatment of inherited genetic diseases
Despite significant improvements in gene therapy in recent years, there are still major drawbacks such as the lack of development of more accessible gene therapies for those with inherited genetic diseases due to a missing or defective gene or gene product. For those individuals, there are limited individualized therapies geared toward their genetic makeup. Weidong… Read more »