Four Indiana University-led technologies and methods, spanning the fields of electrical engineering, medicine and music, recently received patents from the U.S. Patent and Trademark Office. Below is information about each patent.
Patent issued to IU innovation method for treating clinical conditions through the use of hematopoietic stem cells:
The U.S. Patent and Trademark Office has issued a patent for a method developed by a team of IU School of Medicine researchers, including the late Hal Broxmeyer, Maegan Capitano, Scott Cooper and Qingchun Cai. The method helps prevent, reduce resistance to the treatment of, and diagnose conditions associated with an insufficient quantity or quality of hematopoietic stem cells and differentiated blood cells. The conditions can include malignant and nonmalignant cancers, autoimmune diseases and hereditary skeletal dysplasias.
Patent issued for ultra-high cathode materials for lithium-ion batteries:
The U.S. Patent and Trademark Office has issued a patent for cathode active materials for lithium-ion batteries and methods for producing them developed by Jian Xie, a professor of medical engineering at the Purdue School of Engineering and Technology at IUPUI. The new materials achieve improved electrochemical performance, electrical conductivity and structural stability.
Patent issued to IU innovation for acoustical amplification of musical instruments:
The U.S. Patent and Trademark Office has issued a patent for a resonance podium that amplifies acoustics for musical instruments developed by Jamie Tagg, an associate professor of audio engineering and sound production at the IU Jacobs School of Music. The resonance podium supports a performer playing a musical instrument and projects structurally transmitted vibrations for acoustical amplification. Tagg’s innovation has won numerous awards, including a $20,000 Fall Regional Pre-Seed award at the 2022 Elevate Nexus Southern Regional Pitch Competition.
Patent issued to method for treating HPV infections:
The U.S. Patent and Trademark Office has issued a patent for compositions, compounds, formulations and methods developed by Elliot Androphy and Samy Meroueh for treating HPV infections including pre-malignant infections and cancer. Compounds that covalently bind to the HPV E6 protein and block its activity are disclosed. Androphy is a professor of dermatology, microbiology and immunology, and anatomy, cell biology and physiology at the IU School of Medicine, as well as a member of the IU Melvin and Bren Simon Comprehensive Cancer Center. Meroueh recently joined the University of Illinois after serving 18 years as a professor of biochemistry and molecular biology at the IU School of Medicine and a member of the IU Simon Comprehensive Cancer Center. Androphy and Meroueh also are two of the founders of Indianapolis-based Kovina Therapeutics, a portfolio company of IU Ventures, which invests in and supports IU-affiliated early-stage companies.
These innovations were disclosed to the IU Innovation and Commercialization Office. The mission of the office is to transfer IU innovations from lab to market for public benefit and global impact. The office files patents to facilitate commercialization of the innovation. IU personnel can disclose an invention online.
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