Five Indiana University researchers have received patents from the U.S. Patent and Trademark Office for cutting-edge methods and technologies developed at IU. Their innovations include a treatment for bacterial infections, and methods for neural audio coding, audio signal encoding and decoding, correcting errors in depth estimation models, and collecting and detecting chemical evidence from surfaces.
These innovations were disclosed to the IU Innovation and Commercialization Office. The mission of the office is to transfer IU innovations from lab to market for public benefit and global impact. The office files patents to facilitate commercialization of the innovation. IU personnel can disclose an invention online.
Below is information about each of the patents.
Patent issued for the use of bactericidal peptides:
The U.S. Patent and Trademark Office has issued a patent for a method created by C. Cheng Kao, a faculty researcher at the Department of Molecular and Cellular Biochemistry in the IU Bloomington College of Arts and Sciences, for treating bacterial infections using compositions comprising of antimicrobial peptides. The peptide can be dissolved in aqueous buffer and applied to wounds in order to prevent bacterial infections.
Patent issued to IU methods for neural audio coding and audio signal encoding and decoding:
The U.S. Patent and Trademark Office has issued a patent for a method created by Minje Kim, associate professor of intelligent systems engineering at the IU Luddy School of Informatics, Computing and Engineering, for neural audio coding. The method presents psychoacoustic calibration schemes to redefine the loss functions of neural audio coding systems so that the decoded signals resemble the original.
The U.S. Patent and Trademark Office also issued a patent for Kim’s audio signal encoding and decoding method. The method transfers an encoded signal output from each layer to a decoder using a neural network model to increase coding quality. Kim has an extensive portfolio in audio and speech technologies; this is the latest patent issued in collaboration with the Electronics and Telecommunications Research Institute in South Korea, one of the world’s leading research institutes in the wireless communication domain.
Patent issued for method for correcting errors in depth estimation models:
The U.S Patent and Trademark Office has issued a patent for a method created by David Crandall, Luddy Professor of Computer Science at the IU Luddy School of Informatics, Computing and Engineering, and IU-affiliated researchers Jagpreet Chawla, Nikhil Thakurdesai, Anuj Godase and Md Reza for correcting errors in depth information estimated from utilizing a single or plurality of two-dimensional images. The method minimizes errors in estimated depth information to improve the quality of a reconstructed 3D image. Crandall also directs the Luddy Artificial Intelligence Center and the Center for Machine Learning at the Luddy School.
Patent issued for method for collection and detection of chemical evidence from surfaces:
The U.S. Patent and Trademark Office has issued a patent for a method created by Nicholas Manicke that combines paper spray mass spectrometry with the use of a pressure sensitive adhesive (PSA) coated paper. Manicke is an associate professor of chemistry and chemical biology, and forensic and investigative sciences at the IUPUI School of Science. The suspected contaminated surface is brought into contact with the PSA paper, and the particles and residues will adhere to the surface to be later analyzed to improve detection of these substances.
Watch a video spotlighting Manicke’s research, which focuses on developing new ways to apply mass spectrometry to challenges in biomedical research and clinical testing, forensic science, homeland security and food safety.
Bri Heron, technology marketing manager at Indiana University’s Innovation and Commercialization Office, contributed to this story.