Technology Commercialization

The U.S. Patent and Trademark Office has issued a patent on an innovation that could improve results of proton beam therapy during cancer treatments. Although radiation is harmful to all tissues, malignant or healthy, most cancer cells lack control over DNA repair mechanisms. A challenge to radiotherapy in treating cancer is minimizing damage to normal… Read more »

The U.S. Patent and Trademark Office has issued a patent on innovations related to cystic kidney disease. The innovation was created by Robert Bacallao of Indiana University School of Medicine, and James A. Glazier and Sherry G. Clendenon of IU Bloomington. Autosomal dominant polycystic kidney disease is among the most common inherited human diseases, with… Read more »

The U.S. Patent and Trademark Office has issued a patent on innovations that could diagnose and treat lung diseases, including pulmonary emphysema. The innovations were created by Matthias A. Clauss of the Indiana University School of Medicine. More than 3.1 million Americans have been diagnosed with emphysema. Emphysema and chronic bronchitis are the two components… Read more »

The U.S. Patent and Trademark Office has issued a patent on a system and method for monitoring nerve activity. The innovations were created by Dr. Peng-Sheng Chen and Shien-Fong Lin of the Indiana University School of Medicine. Many diagnostic and treatment methods in the fields of medicine and biology rely on measurements of nerve activity… Read more »

The U.S. Patent and Trademark Office has issued a patent on innovations that could improve therapies to repair cartilage damage. Dr. Stephen B. Trippel of the Indiana University School of Medicine created the molecules that are part of this innovation. Articular cartilage damage is a major cause of disability in the form of arthritis and… Read more »

The U.S. Patent and Trademark Office has issued a patent on molecules created by Cheng Kao of Indiana University Bloomington. Kao has developed antimicrobial peptides, sometimes called bacteriocidal peptides, that diminish detrimental pro-inflammatory responses and direct killing of microbes. The innovation was disclosed to the IU Innovation and Commercialization Office. The mission of the office… Read more »

The U.S. Patent and Trademark Office has issued a patent on combination therapies that could treat spinal muscular atrophy. The therapies were created by Dr. Elliot J. Androphy of the Indiana University School of Medicine. Spinal muscular atrophy is a genetic neurological disorder that results from loss of function of cells in the spinal cord…. Read more »

The U.S. Patent and Trademark Office has issued a patent on a stent design that could be assembled in a modular fashion to treat arterial or vascular disease. The inventor is Raghu L. Motaganahalli of the Indiana University School of Medicine. Endovascular stents can be delivered noninvasively to treat aneurysms, but traditional designs do not… Read more »

The U.S. Patent and Trademark Office has issued a patent on a microinverter designed at IUPUI that can be installed to a solar panel with a single fastener. The patent was awarded to Euzeli Cipriano dos Santos of the Purdue School of Engineering and Technology at IUPUI. Microinverters convert direct current from solar panels to… Read more »

The U.S. Patent and Trademark Office has issued a patent on compounds discovered at Indiana University Bloomington that could have an effect against the hepatitis B virus. Hepatitis B (HBV) causes viral hepatitis that can further lead to chronic liver disease and increase the risk of liver cirrhosis and liver cancer. Worldwide, about 2 billion… Read more »