The U.S. Patent and Trademark Office has issued a patent on an innovation to improve upon therapeutics that pertain to controlling protein function. More than two dozen inhibitors of disease-associated enzymes have been developed and approved for clinical use. They are considered invaluable in illuminating the mechanism of these diseases and providing novel therapeutics. But… Read more »

The U.S. Patent and Trademark Office has issued a patent on an innovation to improve the process of paper-spray mass spectrometry. The innovation was created by Nicholas Manicke of IUPUI. Paper-spray mass spectrometry improves upon traditional mass spectrometry methods to identify the amount and type of chemicals present in a sample. Potential applications include patient… Read more »

The U.S. Patent and Trademark Office has issued a patent on a method of noninvasively quantifying in vivo blood flow and flow-artery interaction in an artery. The innovation was created by Huidan “Whitney” Lu of IUPUI and Chen Lin of the Indiana University School of Medicine. Recently, a new method to assess in vivo blood… Read more »

The U.S. Patent and Trademark Office has issued a patent on an innovation to measure or control nerve activity that could be used in the diagnosis and treatment of various cardiac and other medical conditions. The innovation was created by Dr. Peng-Sheng Chen of the Indiana University School of Medicine. Many diagnostic and treatment methods… Read more »

The U.S. Patent and Trademark Office has issued a patent on innovations related to conduit identification tags. The innovation was created by Dr. John T Finnell of the Indiana University School of Medicine. Conduits are used to deliver electrical signals, electrical power or a substance over a distance. Often, numerous conduits are used in close… Read more »

The U.S. Patent and Trademark Office has issued a patent on an innovation that could improve results of proton beam therapy during cancer treatments. Although radiation is harmful to all tissues, malignant or healthy, most cancer cells lack control over DNA repair mechanisms. A challenge to radiotherapy in treating cancer is minimizing damage to normal… Read more »

The U.S. Patent and Trademark Office has issued a patent on innovations related to cystic kidney disease. The innovation was created by Robert Bacallao of Indiana University School of Medicine, and James A. Glazier and Sherry G. Clendenon of IU Bloomington. Autosomal dominant polycystic kidney disease is among the most common inherited human diseases, with… Read more »

The U.S. Patent and Trademark Office has issued a patent on innovations that could diagnose and treat lung diseases, including pulmonary emphysema. The innovations were created by Matthias A. Clauss of the Indiana University School of Medicine. More than 3.1 million Americans have been diagnosed with emphysema. Emphysema and chronic bronchitis are the two components… Read more »

The U.S. Patent and Trademark Office has issued a patent on a system and method for monitoring nerve activity. The innovations were created by Dr. Peng-Sheng Chen and Shien-Fong Lin of the Indiana University School of Medicine. Many diagnostic and treatment methods in the fields of medicine and biology rely on measurements of nerve activity… Read more »

The U.S. Patent and Trademark Office has issued a patent on innovations that could improve therapies to repair cartilage damage. Dr. Stephen B. Trippel of the Indiana University School of Medicine created the molecules that are part of this innovation. Articular cartilage damage is a major cause of disability in the form of arthritis and… Read more »