Five Indiana University researchers have received patents from the U.S. Patent and Trademark Office for cutting-edge technologies and other innovations that they aim to move to market. Below is information about each of the patents.
Patent issued to IU innovation that tests cell response to biochemical agents:
The U.S. Patent and Trademark Office has issued a patent on Trophowell, a platform created by Alexander Gumennik, assistant professor of intelligent systems engineering at the IU Luddy School of Informatics, Computing and Engineering, that tests cell response to biochemical agents.
The cost-effective testing well is used for tissue engineering and can be utilized in the fields of drug discovery and personalized medicine.
Patent issued to IU method that treats salt and water balance diseases:
The U.S. Patent and Trademark Office has issued a patent for a method created by IUPUI School of Science Professor Bonnie Blazer-Yost. The method utilizes SGK1 inhibitors that reduce sodium reabsorption in the blood, thus reducing the development of diseases related to salt and water balance, particularly for hydrocephalus and hypertension. (See a video on Blazer-Yost’s research below.)
The U.S. Patent and Trademark Office has issued a patent for utilizing peptides in treating neurodegenerative diseases to IU School of Dentistry Associate Professor Mythily Srinivasan. Srinivasan developed peptide analogs of a p65 interacting protein that helps suppress inflammation and degeneration for neurodegenerative diseases such as Alzheimer’s disease and multiple sclerosis.
Patent issued to IU School of Medicine treatment for breast cancer:
The U.S. Trademark and Patent Office has recently issued a patent for a combination therapy for breast cancer treatment by Jian-Ting Zhang, adjunct professor of pharmacology and toxicology at the IU School of Medicine.
Zhang’s treatment is combinational use of FDA approved drugs for cancer. The combination of protein pump inhibitors and the PARP inhibitor drastically stops breast cancer cell growth.
Patent issued to an IU novel compressed sensing method and system:
The U.S Trademark and Patent Office has issued a patent for a wireless sensor network developed by IUPUI School of Science Professor Yao Liang. Data acquisition from multi-hop large-scale outdoor wireless sensor networks is challenging, however, Liang’s method drastically improves data acquisition while reducing network transmissions and wireless communication costs.
These innovations were disclosed to the IU Innovation and Commercialization Office. The mission of the office is to transfer IU innovations from lab to market for public benefit and global impact. The office files patents to facilitate commercialization of the innovation. IU personnel can disclose an invention online.
Bri Heron, technology marketing manager at Indiana University’s Innovation and Commercialization Office, contributed this story.