The U.S. Patent and Trademark Office has issued a patent on an innovation to diagnose chronic graft-versus-host disease. The innovation was created by Dr. Sophie Paczesny of the Indiana University School of Medicine.
Chronic graft-versus-host disease occurs after certain transplants when donor immune cells recognize the host tissues as foreign and attack them. The current method to diagnose the disease is using NIH chronic consensus criteria; at the time of diagnosis, patients can already have substantial organ damage.
The IU innovation is a biomarker panel including four biomarkers with a commonly used analytical biochemistry assay to provide an accurate and earlier diagnosis of chronic graft-versus-host disease.
The innovation was disclosed to the IU Innovation and Commercialization Office. The mission of the office is to drive innovation to the market for the benefit of the public, the university and innovators for state, national and global commerce. IU personnel can disclose an invention online.
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