Researchers from our center, in collaboration with State University of New York, Binghamton University and the Instituto Gulbenkian de Ciência developed a mathematical and computational framework to understand how biochemical networks contribute to the evolvability, robustness, and resilience of biological organisms. In a paper in the journal Journal of the Royal Society Interface, Luis Rocha,… Read more »
Tag: Boolean networks
Uncovering the “master switches” of biochemical networks can explain the effects of drugs in the destruction of cancer cells
Researchers from our lab, in collaboration with the Luddy School of Informatics, Computing, and Engineering, the Instituto Gulbenkian de Ciência, and Northeastern University have developed a mathematical framework that increases our ability to explain and control biochemical systems, including those involved in disease. In a paper featured on the cover of the journal Proceedings of the National… Read more »
New Ph.D. Graduate
Congratulations to Santosh Manicka for successfully defending his dissertation entitled “The Role of Canalization in the Spreading of Perturbations in Boolean Networks” on April 24th 2017, Supervised by Luis Rocha. Santosh completed a PhD degree in the Complex Systems track of the Informatics PhD Program.
New Ph.D. Graduate
Congratulations to Alexander Gates for successfully defending his dissertation entitled “The anatomical and effective structure of complex systems” on April 3rd 2017, co-supervised by Randy beer and Luis Rocha. Alex completed a dual-PhD degree in the Complex Systems track of the Informatics PhD Program as well as the Cognitive Science program at Indiana University. Alex… Read more »
Art-Science Installation Musical Morphogenesis
‘Musical Morphogenesis’ is an interactive installation that translates to sound, movement and lights the dynamics behind the development of petals in a flower. It is a collaborative piece developed by designers, architects, musicians and scientists in Luis Rocha‘s CASCI group. The control of this robotic “macroscope” is an implementation of the gene regulatory network of… Read more »
Control of Complex Networks
Network science has allowed us to understand the organization of complex systems across disciplines. However, there is a need to understand how to control them; for example, to identify strategies to revert a diseased cell to a healthy state in cancer treatment. Recent work in the field—based on linear control theory—suggests that the controllability of… Read more »