Take a look at Peter’s first article with our lab where he further narrows the list of potential EphA2 and ephrin-A5 binding partners within the lens! This opens the way for more effective and informative protein work within the lens! Have a read: Spatial-temporal comparison of Eph/Ephrin gene expression in ocular lenses from aging and knockout mice.
Also at ARVO, Dr. Catherine Cheng handed over the chair position of the ARVO AMPC (Annual Meeting Program Committee) to Dr. Xingjun Fan and welcomed the newest LE section member of the committee Dr. Janice Walker. Thank you everyone on the ARVO Annual Meeting Program Committee for their contributions towards making the ARVO meeting successful!
Also at ARVO 2024, Michael presented a poster and moderated a poster session! His first attendance at ARVO was lots of fun as can be seen in the photo with Dr. Chia-Yang Liu, Dr. Yuka Okada, and Dr. Cheng!
Congratulations Gryffin! We’re excited to have you in the lab over the summer!
The Thursday ARVO 2024 symposium, organized and moderated by Dr(s). Dorota Luiza Stankowska and Catherine Cheng, was abundant with great ideas and science! Thank you to the presenters and the attendees for the insightful discussion on biomolecules and drug delivery to the eye!
The mini-symposium, “Biomechanical properties of normal, aging, and pathological eye tissues”, organized by the LE section and moderated by Dr. Bianca Maceo Heilman and Dr. Shizuka Koh, this session was greatly successful! The room was filled such that there were researchers standing along the walls! Thank you to the organizers, moderators, presenters, and attendees for the great work and engagement! Thank you for the great presentations: Dr(s). Kirill Larin, Guiliano Scarcelli, Catherine Cheng, C. Ross Ethier, and Christine Frances Wildsoet!
The lab celebrated by going to Red Lobster! The lab forgot to grab a picture with the cheddar bay biscuits, so here’s a picture from earlier in the day, when our stomachs weren’t ready to burst! Happy Birthday Isaiah!
Not too long ago, Dr. Okada came by to visit and help out with some experiments! We look forward to seeing you again at ARVO Dr. Okada!
Together, with the Fowler and Parreno labs, we have a new article that elucidates novel methods to visualize the peripheral structures in the ocular lens, live and fixed, and methods for image quantification! Video protocols are here: Preparation and Imaging of Murine Ocular Lens Whole Mounts.
Our new paper with Dr. Fowler’s lab shows that rod domain mutations, but not motor domain changes, in myosin IIA lead to changes in ocular lens epithelial cell and fiber cell organization and patterning. These new data add to our knowledge about how equatorial epithelial cells and fiber cells arrange into highly organized hexagon-shaped cells to ensure tight packing and to minimize light scattering. Check our new work here: Disease-related non-muscle myosin IIA D1424N rod domain mutation, but not R702C motor domain mutation, disrupts mouse ocular lens fiber cell alignment and hexagonal packing!
