In this month’s IOVS, you can find Dr. Cheng’s article where she worked with Dr. Fowler’s lab at the University of Delaware to uncover the function of myosin in maintaining the biomechanical properties and transparency of the lens. They showed that the loss of normal myosin filament formation causes abnormal cell shape and disorganization of lens cells. Surprisingly, these defects do not affect lens transparency or stiffness. Read their article here: Nonmuscle Myosin IIA Regulates the Precise Alignment of Hexagonal Eye Lens Epithelial Cells During Fiber Cell Formation and Differentiation.
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